A highly polarized T.sub.H2 bladder response to infection promotes epithelial repair at the expense of preventing new infections

Urinary tract infections (UTIs) typically evoke prompt and vigorous innate bladder immune responses, including extensive exfoliation of the epithelium. To explain the basis for the extraordinarily high recurrence rates of UTIs, we examined adaptive immune responses in mouse bladders. We found that,...

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Veröffentlicht in:Nature immunology 2020-06, Vol.21 (6), p.671
Hauptverfasser: Wu, Jianxuan, Hayes, Byron W, Phoenix, Cassandra, Macias, Gustavo Sosa, Miao, Yuxuan, Choi, Hae Woong, Hughes, Francis M., Jr
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Sprache:eng
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