Pharmacophore and 3d-Qsar Modeling of new 1,3,4-Thiadiazole Derivatives: Specificity to Colorectal Cancer

Interleukin-6 (IL-6) is the new molecular target to treat colorectal cancer (CRC) for investigation of potential lead molecules. The main objective of this study was to develop the three-dimensional quantitative structure – activity relationship (3D-QSAR) and pharmacophore model using data obtained...

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Veröffentlicht in:	Pharmaceutical chemistry journal 2020-04, Vol.54 (1), p.12-25
Hauptverfasser:	Raj, Vinit, Aboumanei, Mohamed H., Rai, Amit, Verma, Suraj P., Singh, Ashok K., Keshari, Amit K., Saha, Sudipta
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Colorectal cancer Interleukins Medicine Molecular dynamics Nuclear energy Organic Chemistry Pharmacology/Toxicology Pharmacy Rankings
Online-Zugang:	Volltext
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