Validated Immunosorbent Surface-Based Determination of Theophylline in Milk
In the present study, an immunosorbent surface-based theophylline determination method was developed and validated. The procedure was tested on milk samples. Theophylline was removed from milk by an immunosorbent surface. The efficiency of theophylline removal was found to be between 95–97%. The pro...
Gespeichert in:
| Veröffentlicht in: | Journal of analytical chemistry (New York, N.Y.) N.Y.), 2020-05, Vol.75 (5), p.640-644 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 644 |
|---|---|
| container_issue | 5 |
| container_start_page | 640 |
| container_title | Journal of analytical chemistry (New York, N.Y.) |
| container_volume | 75 |
| creator | Tugba Tunali Akbay Ipekci, Hazal Yarat, Aysen |
| description | In the present study, an immunosorbent surface-based theophylline determination method was developed and validated. The procedure was tested on milk samples. Theophylline was removed from milk by an immunosorbent surface. The efficiency of theophylline removal was found to be between 95–97%. The proposed method is cost effective and does not require any special equipment. Detection and quantification limits of the proposed method were determined based on the standard deviation of 10 ng/mL theophylline and they were equal 3 and 11 ng/mL, respectively. Results were also validated for precision, accuracy and linearity. |
| doi_str_mv | 10.1134/S1061934820050020 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_webof</sourceid><recordid>TN_cdi_gale_infotracmisc_A622938312</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A622938312</galeid><sourcerecordid>A622938312</sourcerecordid><originalsourceid>FETCH-LOGICAL-c455t-fff69772a8b4254dfe6ea1b675c8597383e81e173bcc6fa688d4dc796013f5de3</originalsourceid><addsrcrecordid>eNqNkV1rFDEUhgdRsFZ_gHcDXolMzcckk1zWVevSFsGt3oZM5mSbOpNskwy2_97UlZbFLUgucsh5npyQt6peY3SEMW3frzDiWNJWEIQYQgQ9qQ4wR6KhWMqnpS7t5q7_vHqR0hVCSArMD6rTH3p0g84w1Mtpmn1IIfbgc72ao9UGmg86ld5HyBAn53V2wdfB1heXEDaXt-PoPNTO1-du_Pmyemb1mODV3_2w-v7508XiS3P29WS5OD5rTMtYbqy1XHYd0aJvCWsHCxw07nnHjGCyo4KCwIA72hvDreZCDO1gOskRppYNQA-rN9t7NzFcz5Cyugpz9GWkIlRKilsm2QO11iMo523IUZvJJaOOOSGyzMGkUM0eag0eoh6DB-vK8Q5_tIcva4DJmb3C2x2hMBlu8lrPKanl6tsui7esiSGlCFZtopt0vFUYqbuY1T8xF0dsnV_QB5uMA2_g3is5M4oEakWpMFm4_CfBRZh9Luq7_1cLTbZ0KoRfQ3z49cdf9xvDlMZ8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2399314595</pqid></control><display><type>article</type><title>Validated Immunosorbent Surface-Based Determination of Theophylline in Milk</title><source>Web of Science - Science Citation Index Expanded - 2020<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><source>SpringerNature Journals</source><creator>Tugba Tunali Akbay ; Ipekci, Hazal ; Yarat, Aysen</creator><creatorcontrib>Tugba Tunali Akbay ; Ipekci, Hazal ; Yarat, Aysen</creatorcontrib><description>In the present study, an immunosorbent surface-based theophylline determination method was developed and validated. The procedure was tested on milk samples. Theophylline was removed from milk by an immunosorbent surface. The efficiency of theophylline removal was found to be between 95–97%. The proposed method is cost effective and does not require any special equipment. Detection and quantification limits of the proposed method were determined based on the standard deviation of 10 ng/mL theophylline and they were equal 3 and 11 ng/mL, respectively. Results were also validated for precision, accuracy and linearity.</description><identifier>ISSN: 1061-9348</identifier><identifier>EISSN: 1608-3199</identifier><identifier>DOI: 10.1134/S1061934820050020</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Analytical Chemistry ; Chemistry ; Chemistry and Materials Science ; Chemistry, Analytical ; Chromatography ; Linearity ; Milk ; Physical Sciences ; Science & Technology ; Theophylline ; Xanthine</subject><ispartof>Journal of analytical chemistry (New York, N.Y.), 2020-05, Vol.75 (5), p.640-644</ispartof><rights>Pleiades Publishing, Ltd. 2020</rights><rights>COPYRIGHT 2020 Springer</rights><rights>Pleiades Publishing, Ltd. 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>2</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000530804800012</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c455t-fff69772a8b4254dfe6ea1b675c8597383e81e173bcc6fa688d4dc796013f5de3</citedby><cites>FETCH-LOGICAL-c455t-fff69772a8b4254dfe6ea1b675c8597383e81e173bcc6fa688d4dc796013f5de3</cites><orcidid>0000-0002-2091-9298</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S1061934820050020$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S1061934820050020$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,27929,27930,28253,41493,42562,51324</link.rule.ids></links><search><creatorcontrib>Tugba Tunali Akbay</creatorcontrib><creatorcontrib>Ipekci, Hazal</creatorcontrib><creatorcontrib>Yarat, Aysen</creatorcontrib><title>Validated Immunosorbent Surface-Based Determination of Theophylline in Milk</title><title>Journal of analytical chemistry (New York, N.Y.)</title><addtitle>J Anal Chem</addtitle><addtitle>J ANAL CHEM</addtitle><description>In the present study, an immunosorbent surface-based theophylline determination method was developed and validated. The procedure was tested on milk samples. Theophylline was removed from milk by an immunosorbent surface. The efficiency of theophylline removal was found to be between 95–97%. The proposed method is cost effective and does not require any special equipment. Detection and quantification limits of the proposed method were determined based on the standard deviation of 10 ng/mL theophylline and they were equal 3 and 11 ng/mL, respectively. Results were also validated for precision, accuracy and linearity.</description><subject>Analytical Chemistry</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Chemistry, Analytical</subject><subject>Chromatography</subject><subject>Linearity</subject><subject>Milk</subject><subject>Physical Sciences</subject><subject>Science & Technology</subject><subject>Theophylline</subject><subject>Xanthine</subject><issn>1061-9348</issn><issn>1608-3199</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>AOWDO</sourceid><recordid>eNqNkV1rFDEUhgdRsFZ_gHcDXolMzcckk1zWVevSFsGt3oZM5mSbOpNskwy2_97UlZbFLUgucsh5npyQt6peY3SEMW3frzDiWNJWEIQYQgQ9qQ4wR6KhWMqnpS7t5q7_vHqR0hVCSArMD6rTH3p0g84w1Mtpmn1IIfbgc72ao9UGmg86ld5HyBAn53V2wdfB1heXEDaXt-PoPNTO1-du_Pmyemb1mODV3_2w-v7508XiS3P29WS5OD5rTMtYbqy1XHYd0aJvCWsHCxw07nnHjGCyo4KCwIA72hvDreZCDO1gOskRppYNQA-rN9t7NzFcz5Cyugpz9GWkIlRKilsm2QO11iMo523IUZvJJaOOOSGyzMGkUM0eag0eoh6DB-vK8Q5_tIcva4DJmb3C2x2hMBlu8lrPKanl6tsui7esiSGlCFZtopt0vFUYqbuY1T8xF0dsnV_QB5uMA2_g3is5M4oEakWpMFm4_CfBRZh9Luq7_1cLTbZ0KoRfQ3z49cdf9xvDlMZ8</recordid><startdate>20200501</startdate><enddate>20200501</enddate><creator>Tugba Tunali Akbay</creator><creator>Ipekci, Hazal</creator><creator>Yarat, Aysen</creator><general>Pleiades Publishing</general><general>Pleiades Publishing Inc</general><general>Springer</general><general>Springer Nature B.V</general><scope>AOWDO</scope><scope>BLEPL</scope><scope>DTL</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><orcidid>https://orcid.org/0000-0002-2091-9298</orcidid></search><sort><creationdate>20200501</creationdate><title>Validated Immunosorbent Surface-Based Determination of Theophylline in Milk</title><author>Tugba Tunali Akbay ; Ipekci, Hazal ; Yarat, Aysen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c455t-fff69772a8b4254dfe6ea1b675c8597383e81e173bcc6fa688d4dc796013f5de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Analytical Chemistry</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Chemistry, Analytical</topic><topic>Chromatography</topic><topic>Linearity</topic><topic>Milk</topic><topic>Physical Sciences</topic><topic>Science & Technology</topic><topic>Theophylline</topic><topic>Xanthine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tugba Tunali Akbay</creatorcontrib><creatorcontrib>Ipekci, Hazal</creatorcontrib><creatorcontrib>Yarat, Aysen</creatorcontrib><collection>Web of Science - Science Citation Index Expanded - 2020</collection><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>CrossRef</collection><collection>Gale In Context: Science</collection><jtitle>Journal of analytical chemistry (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tugba Tunali Akbay</au><au>Ipekci, Hazal</au><au>Yarat, Aysen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Validated Immunosorbent Surface-Based Determination of Theophylline in Milk</atitle><jtitle>Journal of analytical chemistry (New York, N.Y.)</jtitle><stitle>J Anal Chem</stitle><stitle>J ANAL CHEM</stitle><date>2020-05-01</date><risdate>2020</risdate><volume>75</volume><issue>5</issue><spage>640</spage><epage>644</epage><pages>640-644</pages><issn>1061-9348</issn><eissn>1608-3199</eissn><abstract>In the present study, an immunosorbent surface-based theophylline determination method was developed and validated. The procedure was tested on milk samples. Theophylline was removed from milk by an immunosorbent surface. The efficiency of theophylline removal was found to be between 95–97%. The proposed method is cost effective and does not require any special equipment. Detection and quantification limits of the proposed method were determined based on the standard deviation of 10 ng/mL theophylline and they were equal 3 and 11 ng/mL, respectively. Results were also validated for precision, accuracy and linearity.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S1061934820050020</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-2091-9298</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1061-9348 |
| ispartof | Journal of analytical chemistry (New York, N.Y.), 2020-05, Vol.75 (5), p.640-644 |
| issn | 1061-9348 1608-3199 |
| language | eng |
| recordid | cdi_gale_infotracmisc_A622938312 |
| source | Web of Science - Science Citation Index Expanded - 2020<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" />; SpringerNature Journals |
| subjects | Analytical Chemistry Chemistry Chemistry and Materials Science Chemistry, Analytical Chromatography Linearity Milk Physical Sciences Science & Technology Theophylline Xanthine |
| title | Validated Immunosorbent Surface-Based Determination of Theophylline in Milk |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T15%3A04%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_webof&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Validated%20Immunosorbent%20Surface-Based%20Determination%20of%20Theophylline%20in%20Milk&rft.jtitle=Journal%20of%20analytical%20chemistry%20(New%20York,%20N.Y.)&rft.au=Tugba%20Tunali%20Akbay&rft.date=2020-05-01&rft.volume=75&rft.issue=5&rft.spage=640&rft.epage=644&rft.pages=640-644&rft.issn=1061-9348&rft.eissn=1608-3199&rft_id=info:doi/10.1134/S1061934820050020&rft_dat=%3Cgale_webof%3EA622938312%3C/gale_webof%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2399314595&rft_id=info:pmid/&rft_galeid=A622938312&rfr_iscdi=true |