Sickle Cell Anemia Patients Display an Intricate Cellular and Serum Biomarker Network Highlighted by TCD4+CD69+ Lymphocytes, IL-17/MIP-1[beta] IL-12/VEGF, and IL-10/IP-10 Axis

Background. Sickle cell anemia (SCA) is associated with a chronic proinflammatory state characterized by elevated leukocyte count, mortality from severe recurrent infections, and subsequent vasoocclusive complications with leukocyte adhesion to the endothelium and increased plasma levels of inflamma...

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Veröffentlicht in:Journal of Immunology Research 2020-01, Vol.2020
Hauptverfasser: Costa, Allyson Guimaraes, Almeida, Emerson Garcia de, dos Santos, Alicia Patrine C, Malheiro, Adriana, Costa, Thaina Cristina C, Tarrago, Andrea Monteiro, Pontes, Flavia do Carmo Leao, Martins-Filho, Olindo Assis, Martins, Rejane Nina, Soares, Geyse Adriana S, Paula, Erich Vinicius de, Leonardo S., Alexander Junior, Garcia, Nadja Pinto
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Sprache:eng
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