Mitotic slippage is determined by p31.sup.comet and the weakening of the spindle-assembly checkpoint

Mitotic slippage involves cells exiting mitosis without proper chromosome segregation. Although degradation of cyclin B1 during prolonged mitotic arrest is believed to trigger mitotic slippage, its upstream regulation remains obscure. Whether mitotic slippage is caused by APC/C.sup.CDC20 activity th...

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Veröffentlicht in:	Oncogene 2020-03, Vol.39 (13), p.2819
Hauptverfasser:	Lok, Tsun Ming, Wang, Yang, Xu, Wendy Kaichun, Xie, Siwei, Ma, Hoi Tang, Poon, Randy Y. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyclins Enzymes Gene expression Genetic aspects Health aspects Mitosis Regulation
Online-Zugang:	Volltext
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