Oncogenic heterogeneous nuclear ribonucleoprotein D-like modulates the growth and imatinib response of human chronic myeloid leukemia CD34.sup.+ cells via pre-B-cell leukemia homeobox 1

Chronic myeloid leukemia (CML) originates from normal hematopoietic stem cells acquiring BCR-ABL fusion gene, specific BCR-ABL inhibitors (e.g., imatinib mesylate, IM) have greatly improved patient management. However, some patients are still suffering from relapse and drug resistance, which urges b...

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Veröffentlicht in:	Oncogene 2020-01, Vol.39 (2), p.443
Hauptverfasser:	Ji, Dehuan, Zhang, Pengshan, Ma, Wenjuan, Fei, Yiwen, Xue, Wen, Wang, Yu, Zhang, Xiuyan
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic myeloid leukemia Development and progression Drug resistance Growth Hematopoietic stem cells Lymphocytic leukemia RNA
Online-Zugang:	Volltext
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