The inhibitory effect of oridonin on colon cancer was mediated by deactivation of TGF-[beta]l/Smads-PAI-1 signaling pathway in vitro and vivo

Background: Oridonin, the main active component of Rabdosia rubescens, has been demonstrated to have anti-tumor effect on all kinds of cancer cells through various mechanisms and it has shown antitumor activity in some tumors partially via the suppression of TGF-[beta]/Smads signaling pathway. The a...

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Veröffentlicht in:	OncoTargets and therapy 2019-09, p.7467
Hauptverfasser:	Bu, He-Qi, Shen, Feng, Cui, Junhui
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Bone morphogenetic proteins Cancer cells Cancer diagnosis Cancer prevention Cancer research Cancer treatment Carcinoma Colon cancer Colorectal cancer EDTA Genes Genetic research Immunohistochemistry Proteins Surgery Transforming growth factors Tumors
Online-Zugang:	Volltext
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