Propofol inhibits the local activity and connectivity of nuclei in the cortico-reticulo-thalamic loop in rats

Purpose The present study aimed to investigate the effects of different dosages of propofol, that induced different depths of anesthesia, on the local activity and connectivity of nuclei within the cortico-reticulo-thalamic loops, as well as the release of amino acids in those nuclei. Methods The no...

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Veröffentlicht in:	Journal of anesthesia 2019-10, Vol.33 (5), p.572-578
Hauptverfasser:	Yang, Jing, Wang, Wei, Yong, Zheng, Yuan, Weixiu, Zhang, Hong, Mi, Weidong
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia - methods Anesthesiology Animals Critical Care Medicine Electroencephalography Emergency Medicine GABA gamma-Aminobutyric Acid - metabolism Glutamate Glycine Intensive Medicine Medicine & Public Health Original Article Pain Medicine Phenols Propofol Propofol - administration & dosage Rats Rats, Wistar Somatosensory Cortex Wakefulness - drug effects
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