Long non-coding RNA HOTAIR modulates intervertebral disc degenerative changes via Wnt/[beta]-catenin pathway

Background Intervertebral disc degeneration (IDD) has a complicated and enigmatic pathogenic process. Accumulating evidence shows that long non-coding RNAs (LncRNAs) play a role in the pathogenesis of IDD. This study aimed to investigate the expression and role of the LncRNA HOTAIR in IDD pathogenes...

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Veröffentlicht in:	Arthritis research & therapy 2019-09, Vol.21 (1)
Hauptverfasser:	Zhan, Shengfeng, Wang, Kun, Song, Yu, Li, Shuai, Yin, Huipeng, Luo, Rongjin, Liao, Zhiwei, Wu, Xinghuo, Zhang, Yukun, Yang, Cao
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Biological markers Care and treatment Cellular signal transduction Development and progression Genes Health aspects Interleukins Intervertebral disk Proteins RNA RNA interference Scoliosis Spinal diseases
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