Mass spectrometry imaging reveals ganglioside and ceramide localization patterns during cerebellar degeneration in the Npc1.sup.-/- mouse model

Mass spectrometry imaging (MSI) is a powerful tool to perform untargeted mapping of biomolecules in situ. In the current study, we performed matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) to evaluate lipid changes during disease progression (asymptomatic to symptom...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2019-09, Vol.411 (22), p.5659
Hauptverfasser:	Tobias, Fernando, Pathmasiri, Koralege C, Cologna, Stephanie M
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Cell death Gangliosides Mass spectrometry Membrane lipids
Online-Zugang:	Volltext
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