Salidroside protects SH-SY5Y from pathogenic [alpha]-synuclein by promoting cell autophagy via mediation of mTOR/p70S6K signaling

The abnormal aggregation of [alpha]-synuclein ([alpha]-syn), which is an important pathological feature of Parkinson's disease (PD), is cytotoxic to dopaminergic neurons and causes cellular damage and apoptosis. Salidroside (SAL) is the main active component of the traditional Chinese medicine...

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Veröffentlicht in:	Molecular medicine reports 2019-07, Vol.20 (1), p.529
Hauptverfasser:	Chen, Shasha, Cai, Feng, Wang, Jirong, Yang, Zhouxin, Gu, Chi, Wang, Guofu, Mao, Genxiang, Yan, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Asian medicine EDTA Mediation Neurons Proteins Toxicity Traditional Chinese medicine
Online-Zugang:	Volltext
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