N-Pyridyl-Substituted Carboxypiperidine Amides: A New Class of Prokaryote Translation Inhibitors

High-throughput screening identified a new class of antibacterial compounds based on N-pyridyl-substituted p - and m -carboxypiperidine amides. Constructs with the two reporter genes RFP and Katushka2S allowed the detection of compounds that inhibit protein translation against DNA biosynthesis. Some...

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Veröffentlicht in:	Pharmaceutical chemistry journal 2019-06, Vol.53 (3), p.225-229
Hauptverfasser:	Ivanenkov, Ya. A., Komarova (Andreyanova), E. S., Osterman, I. A., Sergiev, P. V., Yamidanov, R. S., Deineka, E. V., Terent’ev, V. A., Fil’kov, G. I., Sofronova, A. A., Mazhuga, A. G., Dontsova, O. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Antibacterial agents Medicine Organic Chemistry Pharmacology/Toxicology Pharmacy Tetracycline Tetracyclines
Online-Zugang:	Volltext
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