Early existence and biochemical evolution characterise acutely synaptotoxic PrP.sup.Sc

Although considerable evidence supports that misfolded prion protein (PrP.sup.Sc) is the principal component of "prions", underpinning both transmissibility and neurotoxicity, clear consensus around a number of fundamental aspects of pathogenesis has not been achieved, including the time o...

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Veröffentlicht in:PLoS pathogens 2019-04, Vol.15 (4)
Hauptverfasser: Foliaki, Simote Totauhelotu, Lewis, Victoria, Islam, Abu Mohammed Taufiqual, Ellett, Laura Jane, Senesi, Matteo, Finkelstein, David Isaac, Roberts, Blaine, Lawson, Victoria A, Adlard, Paul Anthony, Collins, Steven John
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Sprache:eng
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