KLF4 activates NF[kappa]B signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF

Understanding the regulatory mechanisms within esophageal epithelia is essential to gain insight into the pathogenesis of esophageal diseases, which are among the leading causes of morbidity and mortality throughout the world. The zinc-finger transcription factor Krüppel-like factor (KLF4) is implic...

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Veröffentlicht in:	PloS one 2019-04, Vol.14 (4), p.e0215746
Hauptverfasser:	Shaverdashvili, Khvaramze, Padlo, Jennie, Weinblatt, Daniel, Jia, Yang, Jiang, Wenpeng, Rao, Divya, Laczkó, Dorottya, Whelan, Kelly A, Lynch, John P, Muir, Amanda B, Katz, Jonathan P
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding proteins Care and treatment Cellular signal transduction Esophageal cancer Esophageal diseases Esophagitis Genetic aspects Hyperplasia Inflammation Morbidity Protein binding
Online-Zugang:	Volltext
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