Chronic treatment with dexamethasone alters clock gene expression and melatonin synthesis in rat pineal gland at night

Background: Melatonin is a neuroendocrine hormone that regulates many functions involving energy metabolism and behavior in mammals throughout the light/dark cycle. It is considered an output signal of the central circadian clock, located in the suprachiasmatic nucleus of the hypothalamus. Melatonin...

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Veröffentlicht in:	Nature and science of sleep 2018-01, Vol.10, p.203
Hauptverfasser:	Meneses-Santos, Daniela, Buonfiglio, Daniella do Carmo, Peliciari-Garcia, Rodrigo Antonio, Ramos-Lobo, Angela Maria, Souza, Divanizia do Nascimento, Carpinelli, Angelo Rafael, Carvalho, Carla Roberta de Oliveira, Sertie, Rogerio Antonio Laurato, Andreotti, Sandra, Lima, Fabio Bessa, Afeche, Solange Castro, Fioretto, Emerson Ticona, Cipolla-Neto, Jose, Marcal, Anderson Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Body weight Dexamethasone EDTA Enzymes Gene expression Genes Genetic aspects Glucocorticoids Glucose Hormones Hyperglycemia Insulin Melatonin Physiological aspects Steroids (Organic compounds)
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