HIV-1 remission following CCR5[DELTA]32/[DELTA]32 haematopoietic stem-cell transplantation

A cure for HIV-1 remains unattainable as only one case has been reported, a decade ago.sup.1,2. The individual--who is known as the 'Berlin patient'--underwent two allogeneic haematopoietic stem-cell transplantation (HSCT) procedures using a donor with a homozygous mutation in the HIV core...

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Veröffentlicht in:	Nature (London) 2019-04, Vol.568 (7751), p.244
Hauptverfasser:	Gupta, Ravindra K, Abdul-Jawad, Sultan, McCoy, Laura E, Mok, Hoi Ping, Peppa, Dimitra, Salgado, Maria, Martinez-Picado, Javier
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antiretroviral agents Cancer research Care and treatment DNA Efavirenz Emtricitabine Genetic research Hematopoietic stem cell transplantation Highly active antiretroviral therapy HIV HIV infections Lymphocytes Lymphomas Patient outcomes Raltegravir Regression (Disease) Rilpivirine RNA Stem cell transplantation Stem cells Surgery T cells Tumors Vincristine
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