IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle -mediated vessel formation by targeting the [beta]-catenin pathway

The proangiogenic cytokine Interleukin-3 (IL-3) is released by inflammatory cells in breast and ovarian cancer tissue microenvironments and also acts as an autocrine factor for human breast and kidney tumor-derived endothelial cells (TECs). We have previously shown that IL-3-treated endothelial cell...

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Veröffentlicht in:	Oncogene 2018-03, Vol.37 (13), p.1175
Hauptverfasser:	Lombardo, Giusy, Gili, Maddalena, Grange, Cristina, Cavallari, Claudia, Dentelli, Patrizia, Togliatto, Gabriele, Taverna, Daniela
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Cellular signal transduction Endothelium Interleukin-3
Online-Zugang:	Volltext
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