Infectobesity’ in Egyptian adolescent women and its relations to carotid intima-media thickness
Background ‘Infectobesity’ is a new term to describe obesity of infectious origin, such as infection by human adenovirus-36 (Adv36). It appears to be a new concept, evolved over the past 20 years. Visceral obesity is associated with a higher risk of cardiovascular disease. Increased carotid intima–m...
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| Veröffentlicht in: | Journal of the Arab Society for Medical Research 2018-07, Vol.13 (2), p.79-88 |
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| creator | Ibrahim, Amani Mithis, Muhammad Kh Abd al-Rahman, Amani H. Nada, Ayman Sad, Wala al-Tuhami, Muhammad al-Jamal, Hanan A. al-Misri, Sahar A. |
| description | Background
‘Infectobesity’ is a new term to describe obesity of infectious origin, such as infection
by human adenovirus-36 (Adv36). It appears to be a new concept, evolved over the
past 20 years. Visceral obesity is associated with a higher risk of cardiovascular
disease. Increased carotid intima–media thickness (CIMT), a marker of early-onset
atherosclerosis, has been observed in obese children and adolescents. The
present study aims to investigate the relationship between visceral obesity,
CIMT, and Adv36 in female Egyptian adolescents.
Patients and methods
The present study included 90 women aged 12–15 years. It was conducted at the
Medical Excellence Research Center of the National Research Centre, Cairo, Egypt,
during the period between September 2016 and November 2017. Anthropometric
assessment was done. Fasting blood samples were withdrawnforthe measurement of
Qualitative Human Adv36 antibody using a sandwich enzyme-linked immunosorbent
assay.Fastingplasmaglucosewasdetermined calorimetrically,bytheglucoseoxidase
method and insulin level using the solid-phase enzyme-linked immunosorbent assay
and lipid profile. Visceral obesity was measured by an abdominal ultrasound. CIMT for
both carotid arteries were measured by high-resolution echo Doppler.
Results
Girls with visceral obesity (n=26) had higher frequency of increased CIMT at left
(96.2 vs. 75%), right carotid artery (84.6 vs. 73.4%) and Adv36 sero-positive
antibody (69.2 vs. 56.2%) than among those without visceral obesity (n=64).
Among the total samples, visceral obesity had significant positive correlations
with BMI, waist and hip circumference, while it had insignificant correlations with
age, blood pressure (BP), CIMT at right and left carotid arteries, adenovirus and
laboratory findings. CIMT had a significant positive correlation with each other,
insulin resistance and total cholesterol, and significant negative correlations with
high-density lipoprotein and waist circumference. Adv36 had significant negative
correlations with BP (both systolic and diastolic) and significant positive correlation
with insulin level. Adv36 and CIMT had insignificant correlations with each other
and with the anthropometric measurements, BP, visceral obesity, triglycerides, and
low density lipoprotein.
Conclusion
The frequency of Adv36 and increased CIMT at left carotid artery were higher
among girls with visceral obesity than among those without visceral obesity.
However, visceral obesity, CIMT at both right a |
| doi_str_mv | 10.4103/jasmr.jasmr_20_18 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_cross</sourceid><recordid>TN_cdi_gale_infotracmisc_A568081416</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A568081416</galeid><sourcerecordid>A568081416</sourcerecordid><originalsourceid>FETCH-LOGICAL-c282b-d1ea45db3549d5830c4ababb811a47eac00600402dd4038ac14c888d373e93283</originalsourceid><addsrcrecordid>eNp1kcGKFDEQhoO44LDuA-xBCHjusdLJdKePy7DqwoIX9xyqk-rd7HQnSxIZ5uZr-Ho-idFWUdAEKlBV31_UH8YuBWyVAPnmEfOStj-iacEI_YxtWhigka3unrON6HTfqHaQL9hFzo9QT69A9HrD8CZMZEscKfty-vr5C_eBX9-fnorHwNHFmbKlUPgxLlQTwXFfMk80Y_ExZF4it5hi8bUQil-wWch55OXB20OgnF-yswnnTBc_33N29_b64_59c_vh3c3-6raxrW7HxglCtXOj3KnB7bQEq3DEcdRCoOoJLUAHoKB1ToHUaIWyWmsne0lD3VOes9er7j3OZHyYYkloF5-tudp1GrRQoqtd23901eto8TYGmnzN_wWIFbAp5pxoMk-pbplORoD57r5Zff_D_crsV-YY50IpH-ZPR0qmGnMI8fh_0PSDMb8-pKq8WlWojqMJfw8eQAxayW8w7p52</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Infectobesity’ in Egyptian adolescent women and its relations to carotid intima-media thickness</title><source>Medknow Open Access Medical Journals</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Ibrahim, Amani ; Mithis, Muhammad Kh ; Abd al-Rahman, Amani H. ; Nada, Ayman ; Sad, Wala ; al-Tuhami, Muhammad ; al-Jamal, Hanan A. ; al-Misri, Sahar A.</creator><creatorcontrib>Ibrahim, Amani ; Mithis, Muhammad Kh ; Abd al-Rahman, Amani H. ; Nada, Ayman ; Sad, Wala ; al-Tuhami, Muhammad ; al-Jamal, Hanan A. ; al-Misri, Sahar A.</creatorcontrib><description>Background
‘Infectobesity’ is a new term to describe obesity of infectious origin, such as infection
by human adenovirus-36 (Adv36). It appears to be a new concept, evolved over the
past 20 years. Visceral obesity is associated with a higher risk of cardiovascular
disease. Increased carotid intima–media thickness (CIMT), a marker of early-onset
atherosclerosis, has been observed in obese children and adolescents. The
present study aims to investigate the relationship between visceral obesity,
CIMT, and Adv36 in female Egyptian adolescents.
Patients and methods
The present study included 90 women aged 12–15 years. It was conducted at the
Medical Excellence Research Center of the National Research Centre, Cairo, Egypt,
during the period between September 2016 and November 2017. Anthropometric
assessment was done. Fasting blood samples were withdrawnforthe measurement of
Qualitative Human Adv36 antibody using a sandwich enzyme-linked immunosorbent
assay.Fastingplasmaglucosewasdetermined calorimetrically,bytheglucoseoxidase
method and insulin level using the solid-phase enzyme-linked immunosorbent assay
and lipid profile. Visceral obesity was measured by an abdominal ultrasound. CIMT for
both carotid arteries were measured by high-resolution echo Doppler.
Results
Girls with visceral obesity (n=26) had higher frequency of increased CIMT at left
(96.2 vs. 75%), right carotid artery (84.6 vs. 73.4%) and Adv36 sero-positive
antibody (69.2 vs. 56.2%) than among those without visceral obesity (n=64).
Among the total samples, visceral obesity had significant positive correlations
with BMI, waist and hip circumference, while it had insignificant correlations with
age, blood pressure (BP), CIMT at right and left carotid arteries, adenovirus and
laboratory findings. CIMT had a significant positive correlation with each other,
insulin resistance and total cholesterol, and significant negative correlations with
high-density lipoprotein and waist circumference. Adv36 had significant negative
correlations with BP (both systolic and diastolic) and significant positive correlation
with insulin level. Adv36 and CIMT had insignificant correlations with each other
and with the anthropometric measurements, BP, visceral obesity, triglycerides, and
low density lipoprotein.
Conclusion
The frequency of Adv36 and increased CIMT at left carotid artery were higher
among girls with visceral obesity than among those without visceral obesity.
However, visceral obesity, CIMT at both right and left carotid arteries, and
Adv36 had insignificant correlations with each other</description><identifier>ISSN: 1687-4293</identifier><identifier>EISSN: 2090-3286</identifier><identifier>DOI: 10.4103/jasmr.jasmr_20_18</identifier><language>eng</language><publisher>Cairo, Egypt: Arab Society for Medical Research</publisher><subject>Cardiovascular diseases ; Complications and side effects ; Health aspects ; Obesity ; Risk factors ; Youth</subject><ispartof>Journal of the Arab Society for Medical Research, 2018-07, Vol.13 (2), p.79-88</ispartof><rights>COPYRIGHT 2018 Medknow Publications and Media Pvt. Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c282b-d1ea45db3549d5830c4ababb811a47eac00600402dd4038ac14c888d373e93283</citedby><cites>FETCH-LOGICAL-c282b-d1ea45db3549d5830c4ababb811a47eac00600402dd4038ac14c888d373e93283</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27458,27924,27925</link.rule.ids></links><search><creatorcontrib>Ibrahim, Amani</creatorcontrib><creatorcontrib>Mithis, Muhammad Kh</creatorcontrib><creatorcontrib>Abd al-Rahman, Amani H.</creatorcontrib><creatorcontrib>Nada, Ayman</creatorcontrib><creatorcontrib>Sad, Wala</creatorcontrib><creatorcontrib>al-Tuhami, Muhammad</creatorcontrib><creatorcontrib>al-Jamal, Hanan A.</creatorcontrib><creatorcontrib>al-Misri, Sahar A.</creatorcontrib><title>Infectobesity’ in Egyptian adolescent women and its relations to carotid intima-media thickness</title><title>Journal of the Arab Society for Medical Research</title><description>Background
‘Infectobesity’ is a new term to describe obesity of infectious origin, such as infection
by human adenovirus-36 (Adv36). It appears to be a new concept, evolved over the
past 20 years. Visceral obesity is associated with a higher risk of cardiovascular
disease. Increased carotid intima–media thickness (CIMT), a marker of early-onset
atherosclerosis, has been observed in obese children and adolescents. The
present study aims to investigate the relationship between visceral obesity,
CIMT, and Adv36 in female Egyptian adolescents.
Patients and methods
The present study included 90 women aged 12–15 years. It was conducted at the
Medical Excellence Research Center of the National Research Centre, Cairo, Egypt,
during the period between September 2016 and November 2017. Anthropometric
assessment was done. Fasting blood samples were withdrawnforthe measurement of
Qualitative Human Adv36 antibody using a sandwich enzyme-linked immunosorbent
assay.Fastingplasmaglucosewasdetermined calorimetrically,bytheglucoseoxidase
method and insulin level using the solid-phase enzyme-linked immunosorbent assay
and lipid profile. Visceral obesity was measured by an abdominal ultrasound. CIMT for
both carotid arteries were measured by high-resolution echo Doppler.
Results
Girls with visceral obesity (n=26) had higher frequency of increased CIMT at left
(96.2 vs. 75%), right carotid artery (84.6 vs. 73.4%) and Adv36 sero-positive
antibody (69.2 vs. 56.2%) than among those without visceral obesity (n=64).
Among the total samples, visceral obesity had significant positive correlations
with BMI, waist and hip circumference, while it had insignificant correlations with
age, blood pressure (BP), CIMT at right and left carotid arteries, adenovirus and
laboratory findings. CIMT had a significant positive correlation with each other,
insulin resistance and total cholesterol, and significant negative correlations with
high-density lipoprotein and waist circumference. Adv36 had significant negative
correlations with BP (both systolic and diastolic) and significant positive correlation
with insulin level. Adv36 and CIMT had insignificant correlations with each other
and with the anthropometric measurements, BP, visceral obesity, triglycerides, and
low density lipoprotein.
Conclusion
The frequency of Adv36 and increased CIMT at left carotid artery were higher
among girls with visceral obesity than among those without visceral obesity.
However, visceral obesity, CIMT at both right and left carotid arteries, and
Adv36 had insignificant correlations with each other</description><subject>Cardiovascular diseases</subject><subject>Complications and side effects</subject><subject>Health aspects</subject><subject>Obesity</subject><subject>Risk factors</subject><subject>Youth</subject><issn>1687-4293</issn><issn>2090-3286</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp1kcGKFDEQhoO44LDuA-xBCHjusdLJdKePy7DqwoIX9xyqk-rd7HQnSxIZ5uZr-Ho-idFWUdAEKlBV31_UH8YuBWyVAPnmEfOStj-iacEI_YxtWhigka3unrON6HTfqHaQL9hFzo9QT69A9HrD8CZMZEscKfty-vr5C_eBX9-fnorHwNHFmbKlUPgxLlQTwXFfMk80Y_ExZF4it5hi8bUQil-wWch55OXB20OgnF-yswnnTBc_33N29_b64_59c_vh3c3-6raxrW7HxglCtXOj3KnB7bQEq3DEcdRCoOoJLUAHoKB1ToHUaIWyWmsne0lD3VOes9er7j3OZHyYYkloF5-tudp1GrRQoqtd23901eto8TYGmnzN_wWIFbAp5pxoMk-pbplORoD57r5Zff_D_crsV-YY50IpH-ZPR0qmGnMI8fh_0PSDMb8-pKq8WlWojqMJfw8eQAxayW8w7p52</recordid><startdate>20180701</startdate><enddate>20180701</enddate><creator>Ibrahim, Amani</creator><creator>Mithis, Muhammad Kh</creator><creator>Abd al-Rahman, Amani H.</creator><creator>Nada, Ayman</creator><creator>Sad, Wala</creator><creator>al-Tuhami, Muhammad</creator><creator>al-Jamal, Hanan A.</creator><creator>al-Misri, Sahar A.</creator><general>Arab Society for Medical Research</general><general>Wolters Kluwer India Pvt. Ltd</general><general>Medknow Publications and Media Pvt. Ltd</general><scope>ADJCN</scope><scope>AGZBS</scope><scope>AHFXO</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20180701</creationdate><title>Infectobesity’ in Egyptian adolescent women and its relations to carotid intima-media thickness</title><author>Ibrahim, Amani ; Mithis, Muhammad Kh ; Abd al-Rahman, Amani H. ; Nada, Ayman ; Sad, Wala ; al-Tuhami, Muhammad ; al-Jamal, Hanan A. ; al-Misri, Sahar A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282b-d1ea45db3549d5830c4ababb811a47eac00600402dd4038ac14c888d373e93283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Cardiovascular diseases</topic><topic>Complications and side effects</topic><topic>Health aspects</topic><topic>Obesity</topic><topic>Risk factors</topic><topic>Youth</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ibrahim, Amani</creatorcontrib><creatorcontrib>Mithis, Muhammad Kh</creatorcontrib><creatorcontrib>Abd al-Rahman, Amani H.</creatorcontrib><creatorcontrib>Nada, Ayman</creatorcontrib><creatorcontrib>Sad, Wala</creatorcontrib><creatorcontrib>al-Tuhami, Muhammad</creatorcontrib><creatorcontrib>al-Jamal, Hanan A.</creatorcontrib><creatorcontrib>al-Misri, Sahar A.</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>قاعدة العلوم الاجتماعية - e-Marefa Social Sciences</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>CrossRef</collection><jtitle>Journal of the Arab Society for Medical Research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ibrahim, Amani</au><au>Mithis, Muhammad Kh</au><au>Abd al-Rahman, Amani H.</au><au>Nada, Ayman</au><au>Sad, Wala</au><au>al-Tuhami, Muhammad</au><au>al-Jamal, Hanan A.</au><au>al-Misri, Sahar A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Infectobesity’ in Egyptian adolescent women and its relations to carotid intima-media thickness</atitle><jtitle>Journal of the Arab Society for Medical Research</jtitle><date>2018-07-01</date><risdate>2018</risdate><volume>13</volume><issue>2</issue><spage>79</spage><epage>88</epage><pages>79-88</pages><issn>1687-4293</issn><eissn>2090-3286</eissn><abstract>Background
‘Infectobesity’ is a new term to describe obesity of infectious origin, such as infection
by human adenovirus-36 (Adv36). It appears to be a new concept, evolved over the
past 20 years. Visceral obesity is associated with a higher risk of cardiovascular
disease. Increased carotid intima–media thickness (CIMT), a marker of early-onset
atherosclerosis, has been observed in obese children and adolescents. The
present study aims to investigate the relationship between visceral obesity,
CIMT, and Adv36 in female Egyptian adolescents.
Patients and methods
The present study included 90 women aged 12–15 years. It was conducted at the
Medical Excellence Research Center of the National Research Centre, Cairo, Egypt,
during the period between September 2016 and November 2017. Anthropometric
assessment was done. Fasting blood samples were withdrawnforthe measurement of
Qualitative Human Adv36 antibody using a sandwich enzyme-linked immunosorbent
assay.Fastingplasmaglucosewasdetermined calorimetrically,bytheglucoseoxidase
method and insulin level using the solid-phase enzyme-linked immunosorbent assay
and lipid profile. Visceral obesity was measured by an abdominal ultrasound. CIMT for
both carotid arteries were measured by high-resolution echo Doppler.
Results
Girls with visceral obesity (n=26) had higher frequency of increased CIMT at left
(96.2 vs. 75%), right carotid artery (84.6 vs. 73.4%) and Adv36 sero-positive
antibody (69.2 vs. 56.2%) than among those without visceral obesity (n=64).
Among the total samples, visceral obesity had significant positive correlations
with BMI, waist and hip circumference, while it had insignificant correlations with
age, blood pressure (BP), CIMT at right and left carotid arteries, adenovirus and
laboratory findings. CIMT had a significant positive correlation with each other,
insulin resistance and total cholesterol, and significant negative correlations with
high-density lipoprotein and waist circumference. Adv36 had significant negative
correlations with BP (both systolic and diastolic) and significant positive correlation
with insulin level. Adv36 and CIMT had insignificant correlations with each other
and with the anthropometric measurements, BP, visceral obesity, triglycerides, and
low density lipoprotein.
Conclusion
The frequency of Adv36 and increased CIMT at left carotid artery were higher
among girls with visceral obesity than among those without visceral obesity.
However, visceral obesity, CIMT at both right and left carotid arteries, and
Adv36 had insignificant correlations with each other</abstract><cop>Cairo, Egypt</cop><pub>Arab Society for Medical Research</pub><doi>10.4103/jasmr.jasmr_20_18</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1687-4293 |
| ispartof | Journal of the Arab Society for Medical Research, 2018-07, Vol.13 (2), p.79-88 |
| issn | 1687-4293 2090-3286 |
| language | eng |
| recordid | cdi_gale_infotracmisc_A568081416 |
| source | Medknow Open Access Medical Journals; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Cardiovascular diseases Complications and side effects Health aspects Obesity Risk factors Youth |
| title | Infectobesity’ in Egyptian adolescent women and its relations to carotid intima-media thickness |
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