sup.1H-NMR and MALDI-TOF MS as metabolomic quality control tests to classify platelet derived medium additives for GMP compliant cell expansion procedures

Ex vivo cell expansion under Good Manufacturing Practice (GMP) guidelines can be performed using medium additives containing human growth factors from platelets. These products can differently affect proliferation of adipose mesenchymal stromal stem cells (ASC). Qualification of medium additive perf...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PloS one 2018-09, Vol.13 (9), p.e0203048
Hauptverfasser:	Agostini, Francesco, Ruzza, Marta, Corpillo, Davide, Biondi, Luca, Acquadro, Elena, Canepa, Barbara, Viale, Alessandra, Battiston, Monica, Serra, Fabrizio, Aime, Silvio, Mazzucato, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell proliferation Good manufacturing practice Growth Mass spectrometry Nuclear magnetic resonance spectroscopy Stem cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!