Recombinant MHC Tetramers for Isolation of Virus-Specific [CD8.sup.+] Cells from Healthy Donors: Potential Approach for Cell Therapy of Posttransplant Cytomegalovirus Infection

Patients undergoing allogeneic hematopoietic stem cell transplantation have a high risk of cytomegalovirus reactivation, which in the absence of T-cell immunity can result in the development of an acute inflammatory reaction and damage of internal organs. Transfusion of the virus-specific donor T-ly...

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Veröffentlicht in:Biochemistry (Moscow) 2016-11, Vol.81 (11), p.1371
Hauptverfasser: Vdovin, A.S, Filkin, S.Y, Yefimova, P.R, Sheetikov, S.A, Kapranov, N.M, Davydova, Y.O, Egorov, E.S, Khamaganova, E.G, Drokov, M.Y, Kuzmina, L.A, Parovichnikova, E.N, Efimov, G.A, Savchenko, V.G
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Sprache:eng
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