Functional and genomic analyses reveal therapeutic potential of targeting [beta]-catenin/CBP activity in head and neck cancer

Background Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy characterized by tumor heterogeneity, locoregional metastases, and resistance to existing treatments. Although a number of genomic and molecular alterations associated with HNSCC have been identified, they have had...

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Veröffentlicht in:	Genome medicine 2018-07, Vol.10 (1)
Hauptverfasser:	Kartha, Vinay K, Alamoud, Khalid A, Sadykov, Khikmet, Nguyen, Bach-Cuc, Laroche, Fabrice, Feng, Hui, Lee, Jina, Pai, Sara I, Varelas, Xaralabos, Egloff, Ann Marie, Snyder-Cappione, Jennifer E, Belkina, Anna C, Bais, Manish V, Monti, Stefano, Kukuruzinska, Maria A
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Cellular signal transduction Drug resistance Genetic aspects Genomics Head and neck cancer
Online-Zugang:	Volltext
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