Human [CD30.sup.+] B cells represent a unique subset related to Hodgkin lymphoma cells

Very few B cells in germinal centers (GCs) and extrafollicular (EF) regions of lymph nodes express CD30. Their specific features and relationship to [CD30.sup.-]expressing Hodgkin and Reed/Sternberg (HRS) cells of Hodgkin lymphoma are unclear but highly relevant, because numerous patients with lymph...

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Veröffentlicht in:	The Journal of clinical investigation 2018-07, Vol.128 (7), p.2996
Hauptverfasser:	Weniger, Marc A, Tiacci, Enrico, Schneider, Stefanie, Arnolds, Judith, Ruschenbaum, Sabrina, Duppach, Janine, Seifert, Marc, Doring, Claudia, Hansmann, Martin-Leo, Kuppers, Ralf
Format:	Artikel
Sprache:	eng
Schlagworte:	B cells Gene expression Genetic aspects Hodgkin's disease Lymph nodes Membrane proteins Physiological aspects Risk factors
Online-Zugang:	Volltext
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