Doxorubicin-induced cardiotoxicity is suppressed by estrous-staged treatment and exogenous 17[beta]-estradiol in female tumor-bearing spontaneously hypertensive rats

Background Doxorubicin (DOX), an anthracycline therapeutic, is widely used to treat a variety of cancer types and known to induce cardiomyopathy in a time and dose-dependent manner. Postmenopausal and hypertensive females are two high-risk groups for developing adverse effects following DOX treatmen...

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Veröffentlicht in:	Biology of sex differences 2018-06, Vol.9 (1)
Hauptverfasser:	Pokrzywinski, Kaytee L, Biel, Thomas G, Rosen, Elliot T, Bonanno, Julia L, Aryal, Baikuntha, Mascia, Francesca, Moshkelani, Delaram, Mog, Steven, Rao, V. Ashutosh
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthracyclines Breast tumors Care and treatment Dosage and administration Doxorubicin Tamoxifen Troponin
Online-Zugang:	Volltext
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