An adenosine A1R-A2aR imbalance regulates low glucose/hypoxia-induced microglial activation, thereby contributing to oligodendrocyte damage through NF-[KAPPA]B and CREB phosphorylation

Microglial activation-mediated inflammatory damage to oligodendrocytes is a key step in the etiology of ischemic white matter lesions. The adenosine A1 receptor (A1R) and adenosine A2a receptor (A2aR) have been reported to regulate the activation of microglia, however, the underlying mechanisms rema...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of molecular medicine 2018-06, Vol.41 (6), p.3559
Hauptverfasser:	Huang, Wen, Bai, Shunjie, Zuo, Xuzheng, Tang, Weiju, Chen, Pengfei, Chen, Xiuying, Wang, Gong, Wang, Haoxiang, Xie, Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain injuries Care and treatment Cell receptors Development and progression Genetic aspects Health aspects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!