EWSFLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma
Gespeichert in:
Veröffentlicht in: | Nature (London) 2018-03, Vol.555 (7696), p.387 |
---|---|
Hauptverfasser: | , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | 7696 |
container_start_page | 387 |
container_title | Nature (London) |
container_volume | 555 |
creator | Gorthi, Aparna Romero, July Carolina Loranc, Eva Cao, Lin Lawrence, Liesl A Goodale, Elicia Iniguez, Amanda Balboni Bernard, Xavier Masamsetti, V. Pragathi Roston, Sydney Lawlor, Elizabeth R Toretsky, Jeffrey A Stegmaier, Kimberly Lessnick, Stephen L Chen, Yidong Bishop, Alexander J. R |
description | |
doi_str_mv | 10.1038/nature25748 |
format | Article |
fullrecord | <record><control><sourceid>gale</sourceid><recordid>TN_cdi_gale_infotracmisc_A531044101</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A531044101</galeid><sourcerecordid>A531044101</sourcerecordid><originalsourceid>FETCH-LOGICAL-g2021-944fdeeb44b5bfd0c40b68f2e47b0bbdb6311b9e0e3ef724c184743c224da9de3</originalsourceid><addsrcrecordid>eNp10N9LwzAQB_AgCs7pk_9A0CeRapKmP_ZYy6aDobBN5ltJ0muJdklNOvTPt6APG1Tu4eD4fI_jELqk5I6SML03ots5YFHC0yM0ojyJAx6nyTEaEcLSgKRhfIrOvH8nhEQ04SP0Nt2sZos5xdooB8KDx50Txiun205bgzuLldh5wMugsbb1WJgSy8aqD_ywzDOKHbRCuz6Pp1_a1NgLp-xWnKOTSjQeLv76GL3Opuv8KVi8PM7zbBHUjDAaTDivSgDJuYxkVRLFiYzTigFPJJGylHFIqZwAgRCqhHFFU57wUDHGSzEpIRyj69-9tWig0Kay_f1qq70qsiikhHNKaK-CAVWDAScaa6DS_fjAXw141erPYh_dDaC-SthqNbj15iDQmw6-u7r_ry_mq-Whvf3fZutN_ryvfwBhM5j8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>EWSFLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma</title><source>SpringerLink Journals</source><source>Nature Journals Online</source><creator>Gorthi, Aparna ; Romero, July Carolina ; Loranc, Eva ; Cao, Lin ; Lawrence, Liesl A ; Goodale, Elicia ; Iniguez, Amanda Balboni ; Bernard, Xavier ; Masamsetti, V. Pragathi ; Roston, Sydney ; Lawlor, Elizabeth R ; Toretsky, Jeffrey A ; Stegmaier, Kimberly ; Lessnick, Stephen L ; Chen, Yidong ; Bishop, Alexander J. R</creator><creatorcontrib>Gorthi, Aparna ; Romero, July Carolina ; Loranc, Eva ; Cao, Lin ; Lawrence, Liesl A ; Goodale, Elicia ; Iniguez, Amanda Balboni ; Bernard, Xavier ; Masamsetti, V. Pragathi ; Roston, Sydney ; Lawlor, Elizabeth R ; Toretsky, Jeffrey A ; Stegmaier, Kimberly ; Lessnick, Stephen L ; Chen, Yidong ; Bishop, Alexander J. R</creatorcontrib><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/nature25748</identifier><language>eng</language><publisher>Nature Publishing Group</publisher><subject>Binding proteins ; Ewing's sarcoma ; Genetic aspects ; Health aspects ; RNA ; Transcription (Genetics)</subject><ispartof>Nature (London), 2018-03, Vol.555 (7696), p.387</ispartof><rights>COPYRIGHT 2018 Nature Publishing Group</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Gorthi, Aparna</creatorcontrib><creatorcontrib>Romero, July Carolina</creatorcontrib><creatorcontrib>Loranc, Eva</creatorcontrib><creatorcontrib>Cao, Lin</creatorcontrib><creatorcontrib>Lawrence, Liesl A</creatorcontrib><creatorcontrib>Goodale, Elicia</creatorcontrib><creatorcontrib>Iniguez, Amanda Balboni</creatorcontrib><creatorcontrib>Bernard, Xavier</creatorcontrib><creatorcontrib>Masamsetti, V. Pragathi</creatorcontrib><creatorcontrib>Roston, Sydney</creatorcontrib><creatorcontrib>Lawlor, Elizabeth R</creatorcontrib><creatorcontrib>Toretsky, Jeffrey A</creatorcontrib><creatorcontrib>Stegmaier, Kimberly</creatorcontrib><creatorcontrib>Lessnick, Stephen L</creatorcontrib><creatorcontrib>Chen, Yidong</creatorcontrib><creatorcontrib>Bishop, Alexander J. R</creatorcontrib><title>EWSFLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma</title><title>Nature (London)</title><subject>Binding proteins</subject><subject>Ewing's sarcoma</subject><subject>Genetic aspects</subject><subject>Health aspects</subject><subject>RNA</subject><subject>Transcription (Genetics)</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp10N9LwzAQB_AgCs7pk_9A0CeRapKmP_ZYy6aDobBN5ltJ0muJdklNOvTPt6APG1Tu4eD4fI_jELqk5I6SML03ots5YFHC0yM0ojyJAx6nyTEaEcLSgKRhfIrOvH8nhEQ04SP0Nt2sZos5xdooB8KDx50Txiun205bgzuLldh5wMugsbb1WJgSy8aqD_ywzDOKHbRCuz6Pp1_a1NgLp-xWnKOTSjQeLv76GL3Opuv8KVi8PM7zbBHUjDAaTDivSgDJuYxkVRLFiYzTigFPJJGylHFIqZwAgRCqhHFFU57wUDHGSzEpIRyj69-9tWig0Kay_f1qq70qsiikhHNKaK-CAVWDAScaa6DS_fjAXw141erPYh_dDaC-SthqNbj15iDQmw6-u7r_ry_mq-Whvf3fZutN_ryvfwBhM5j8</recordid><startdate>20180315</startdate><enddate>20180315</enddate><creator>Gorthi, Aparna</creator><creator>Romero, July Carolina</creator><creator>Loranc, Eva</creator><creator>Cao, Lin</creator><creator>Lawrence, Liesl A</creator><creator>Goodale, Elicia</creator><creator>Iniguez, Amanda Balboni</creator><creator>Bernard, Xavier</creator><creator>Masamsetti, V. Pragathi</creator><creator>Roston, Sydney</creator><creator>Lawlor, Elizabeth R</creator><creator>Toretsky, Jeffrey A</creator><creator>Stegmaier, Kimberly</creator><creator>Lessnick, Stephen L</creator><creator>Chen, Yidong</creator><creator>Bishop, Alexander J. R</creator><general>Nature Publishing Group</general><scope>ATWCN</scope></search><sort><creationdate>20180315</creationdate><title>EWSFLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma</title><author>Gorthi, Aparna ; Romero, July Carolina ; Loranc, Eva ; Cao, Lin ; Lawrence, Liesl A ; Goodale, Elicia ; Iniguez, Amanda Balboni ; Bernard, Xavier ; Masamsetti, V. Pragathi ; Roston, Sydney ; Lawlor, Elizabeth R ; Toretsky, Jeffrey A ; Stegmaier, Kimberly ; Lessnick, Stephen L ; Chen, Yidong ; Bishop, Alexander J. R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g2021-944fdeeb44b5bfd0c40b68f2e47b0bbdb6311b9e0e3ef724c184743c224da9de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Binding proteins</topic><topic>Ewing's sarcoma</topic><topic>Genetic aspects</topic><topic>Health aspects</topic><topic>RNA</topic><topic>Transcription (Genetics)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gorthi, Aparna</creatorcontrib><creatorcontrib>Romero, July Carolina</creatorcontrib><creatorcontrib>Loranc, Eva</creatorcontrib><creatorcontrib>Cao, Lin</creatorcontrib><creatorcontrib>Lawrence, Liesl A</creatorcontrib><creatorcontrib>Goodale, Elicia</creatorcontrib><creatorcontrib>Iniguez, Amanda Balboni</creatorcontrib><creatorcontrib>Bernard, Xavier</creatorcontrib><creatorcontrib>Masamsetti, V. Pragathi</creatorcontrib><creatorcontrib>Roston, Sydney</creatorcontrib><creatorcontrib>Lawlor, Elizabeth R</creatorcontrib><creatorcontrib>Toretsky, Jeffrey A</creatorcontrib><creatorcontrib>Stegmaier, Kimberly</creatorcontrib><creatorcontrib>Lessnick, Stephen L</creatorcontrib><creatorcontrib>Chen, Yidong</creatorcontrib><creatorcontrib>Bishop, Alexander J. R</creatorcontrib><collection>Gale In Context: Middle School</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gorthi, Aparna</au><au>Romero, July Carolina</au><au>Loranc, Eva</au><au>Cao, Lin</au><au>Lawrence, Liesl A</au><au>Goodale, Elicia</au><au>Iniguez, Amanda Balboni</au><au>Bernard, Xavier</au><au>Masamsetti, V. Pragathi</au><au>Roston, Sydney</au><au>Lawlor, Elizabeth R</au><au>Toretsky, Jeffrey A</au><au>Stegmaier, Kimberly</au><au>Lessnick, Stephen L</au><au>Chen, Yidong</au><au>Bishop, Alexander J. R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>EWSFLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma</atitle><jtitle>Nature (London)</jtitle><date>2018-03-15</date><risdate>2018</risdate><volume>555</volume><issue>7696</issue><spage>387</spage><pages>387-</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><pub>Nature Publishing Group</pub><doi>10.1038/nature25748</doi><tpages>387</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0028-0836 |
ispartof | Nature (London), 2018-03, Vol.555 (7696), p.387 |
issn | 0028-0836 1476-4687 |
language | eng |
recordid | cdi_gale_infotracmisc_A531044101 |
source | SpringerLink Journals; Nature Journals Online |
subjects | Binding proteins Ewing's sarcoma Genetic aspects Health aspects RNA Transcription (Genetics) |
title | EWSFLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T05%3A18%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=EWSFLI1%20increases%20transcription%20to%20cause%20R-loops%20and%20block%20BRCA1%20repair%20in%20Ewing%20sarcoma&rft.jtitle=Nature%20(London)&rft.au=Gorthi,%20Aparna&rft.date=2018-03-15&rft.volume=555&rft.issue=7696&rft.spage=387&rft.pages=387-&rft.issn=0028-0836&rft.eissn=1476-4687&rft_id=info:doi/10.1038/nature25748&rft_dat=%3Cgale%3EA531044101%3C/gale%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A531044101&rfr_iscdi=true |