The natural compound Jatrophone interferes with Wnt/[beta]-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer

Metastatic breast cancer is the leading cause of worldwide cancer-related deaths among women. Triple negative breast cancers (TNBC) are highly metastatic and are devoid of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) amplification. TNBCs are...

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Veröffentlicht in:	PloS one 2017-12, Vol.12 (12), p.e0189864
Hauptverfasser:	Fatima, Iram, El-Ayachi, Ikbale, Taotao, Ling, Lillo, M. Angeles, Krutilina, Raya, Seagroves, Tiffany N, Radaszkiewicz, Tomasz W, Hutnan, Miroslav, Bryja, Vitezslav, Krum, Susan A, Rivas, Fatima, Miranda-Carboni, Gustavo A
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Care and treatment Development and progression Gene expression Genetic aspects Health aspects Oncogenes Terpenes
Online-Zugang:	Volltext
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