The IL-1[beta] Receptor Antagonist SER140 Postpones the Onset of Diabetes in Female Nonobese Diabetic Mice

The cytokine interleukin-1[beta] (IL-1[beta]) is known to stimulate proinflammatory immune responses and impair [beta]-cell function and viability, all critical events in the pathogenesis of type 1 diabetes (T1D). Here we evaluate the effect of SER140, a small peptide IL-1[beta] receptor antagonist,...

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Veröffentlicht in:	Journal of Diabetes Research 2016-01, Vol.2016
Hauptverfasser:	Cucak, Helena, Hansen, Gitte, Vrang, Niels, Skarsfeld, Torben, Steiness Eva, Jelsing, Jacob
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood sugar Comparative analysis Diabetes therapy Disease susceptibility Immune response Immunotherapy Interleukins Type 1 diabetes
Online-Zugang:	Volltext
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