Determination of vitamin [K.sub.1] in blood serum by high-performance liquid chromatography
A method is proposed for the determination of vitamin [K.sub.1] concentration in blood serum using HPLC on a Gemini C18 (250 mm x 4.6 mm ID, 5 [micro]m) column and elution with a methanol--acetonitrile--dichloromethane (45 : 50 : 5, v/v) mobile phase at a flow rate of 1 mL/min and detection at 248 n...
Gespeichert in:
| Veröffentlicht in: | Journal of analytical chemistry (New York, N.Y.) N.Y.), 2016-07, Vol.71 (7), p.737 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 7 |
| container_start_page | 737 |
| container_title | Journal of analytical chemistry (New York, N.Y.) |
| container_volume | 71 |
| creator | Sokolova, O.V Potapova, I.A |
| description | A method is proposed for the determination of vitamin [K.sub.1] concentration in blood serum using HPLC on a Gemini C18 (250 mm x 4.6 mm ID, 5 [micro]m) column and elution with a methanol--acetonitrile--dichloromethane (45 : 50 : 5, v/v) mobile phase at a flow rate of 1 mL/min and detection at 248 nm. The limit of detection for the vitamin is 0.5 ng/mL and relative error is 19%. The volume of sample in the column is 100 [micro]L. The method has been applied to the evaluation of vitamin [K.sub.1] deficit in a human body in medical practice. |
| doi_str_mv | 10.1134/S1061934816070157 |
| format | Article |
| fullrecord | <record><control><sourceid>gale</sourceid><recordid>TN_cdi_gale_infotracmisc_A496567850</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A496567850</galeid><sourcerecordid>A496567850</sourcerecordid><originalsourceid>FETCH-LOGICAL-g1390-5d0370a1fdbbddcafb84cee5a060085d8120758441b81dbfb3eb74ae43a320603</originalsourceid><addsrcrecordid>eNptjEtLAzEUhYMoWKs_wF3AlYsZkybzWpb6KhYEq6siJZnczERmJjWZEfvvTdGFhXIX95x7vnMRuqQkppTxmyUlKS0Yz2lKMkKT7AiNgswjRoviOOgQR7v8FJ15_0EIKQI6Qqtb6MG1phO9sR22Gn-ZXgSPV0-xH2RM33EwsrFWYQ9uaLHc4tpUdbQBp61rRVcCbsznYBQua2db0dvKiU29PUcnWjQeLv72GL3d373OHqPF88N8Nl1EFWUFiRJFWEYE1UpKpUqhZc5LgESQlJA8UTmdkCzJOacyp0pqyUBmXABngk0Cw8bo6vdvJRpYm07b3omyNb5cT3mRJmmWJzsqOkBV0IETje1Am3De4-MDfBgFrSkPFq73CoHp4buvxOD9er58-c_-ALzWgok</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Determination of vitamin [K.sub.1] in blood serum by high-performance liquid chromatography</title><source>SpringerLink Journals - AutoHoldings</source><creator>Sokolova, O.V ; Potapova, I.A</creator><creatorcontrib>Sokolova, O.V ; Potapova, I.A</creatorcontrib><description>A method is proposed for the determination of vitamin [K.sub.1] concentration in blood serum using HPLC on a Gemini C18 (250 mm x 4.6 mm ID, 5 [micro]m) column and elution with a methanol--acetonitrile--dichloromethane (45 : 50 : 5, v/v) mobile phase at a flow rate of 1 mL/min and detection at 248 nm. The limit of detection for the vitamin is 0.5 ng/mL and relative error is 19%. The volume of sample in the column is 100 [micro]L. The method has been applied to the evaluation of vitamin [K.sub.1] deficit in a human body in medical practice.</description><identifier>ISSN: 1061-9348</identifier><identifier>EISSN: 1608-3199</identifier><identifier>DOI: 10.1134/S1061934816070157</identifier><language>eng</language><publisher>Springer</publisher><subject>Analysis ; Blood serum ; High performance liquid chromatography ; Vitamin K</subject><ispartof>Journal of analytical chemistry (New York, N.Y.), 2016-07, Vol.71 (7), p.737</ispartof><rights>COPYRIGHT 2016 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Sokolova, O.V</creatorcontrib><creatorcontrib>Potapova, I.A</creatorcontrib><title>Determination of vitamin [K.sub.1] in blood serum by high-performance liquid chromatography</title><title>Journal of analytical chemistry (New York, N.Y.)</title><description>A method is proposed for the determination of vitamin [K.sub.1] concentration in blood serum using HPLC on a Gemini C18 (250 mm x 4.6 mm ID, 5 [micro]m) column and elution with a methanol--acetonitrile--dichloromethane (45 : 50 : 5, v/v) mobile phase at a flow rate of 1 mL/min and detection at 248 nm. The limit of detection for the vitamin is 0.5 ng/mL and relative error is 19%. The volume of sample in the column is 100 [micro]L. The method has been applied to the evaluation of vitamin [K.sub.1] deficit in a human body in medical practice.</description><subject>Analysis</subject><subject>Blood serum</subject><subject>High performance liquid chromatography</subject><subject>Vitamin K</subject><issn>1061-9348</issn><issn>1608-3199</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNptjEtLAzEUhYMoWKs_wF3AlYsZkybzWpb6KhYEq6siJZnczERmJjWZEfvvTdGFhXIX95x7vnMRuqQkppTxmyUlKS0Yz2lKMkKT7AiNgswjRoviOOgQR7v8FJ15_0EIKQI6Qqtb6MG1phO9sR22Gn-ZXgSPV0-xH2RM33EwsrFWYQ9uaLHc4tpUdbQBp61rRVcCbsznYBQua2db0dvKiU29PUcnWjQeLv72GL3d373OHqPF88N8Nl1EFWUFiRJFWEYE1UpKpUqhZc5LgESQlJA8UTmdkCzJOacyp0pqyUBmXABngk0Cw8bo6vdvJRpYm07b3omyNb5cT3mRJmmWJzsqOkBV0IETje1Am3De4-MDfBgFrSkPFq73CoHp4buvxOD9er58-c_-ALzWgok</recordid><startdate>20160701</startdate><enddate>20160701</enddate><creator>Sokolova, O.V</creator><creator>Potapova, I.A</creator><general>Springer</general><scope>ISR</scope></search><sort><creationdate>20160701</creationdate><title>Determination of vitamin [K.sub.1] in blood serum by high-performance liquid chromatography</title><author>Sokolova, O.V ; Potapova, I.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g1390-5d0370a1fdbbddcafb84cee5a060085d8120758441b81dbfb3eb74ae43a320603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Analysis</topic><topic>Blood serum</topic><topic>High performance liquid chromatography</topic><topic>Vitamin K</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sokolova, O.V</creatorcontrib><creatorcontrib>Potapova, I.A</creatorcontrib><collection>Science In Context</collection><jtitle>Journal of analytical chemistry (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sokolova, O.V</au><au>Potapova, I.A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determination of vitamin [K.sub.1] in blood serum by high-performance liquid chromatography</atitle><jtitle>Journal of analytical chemistry (New York, N.Y.)</jtitle><date>2016-07-01</date><risdate>2016</risdate><volume>71</volume><issue>7</issue><spage>737</spage><pages>737-</pages><issn>1061-9348</issn><eissn>1608-3199</eissn><abstract>A method is proposed for the determination of vitamin [K.sub.1] concentration in blood serum using HPLC on a Gemini C18 (250 mm x 4.6 mm ID, 5 [micro]m) column and elution with a methanol--acetonitrile--dichloromethane (45 : 50 : 5, v/v) mobile phase at a flow rate of 1 mL/min and detection at 248 nm. The limit of detection for the vitamin is 0.5 ng/mL and relative error is 19%. The volume of sample in the column is 100 [micro]L. The method has been applied to the evaluation of vitamin [K.sub.1] deficit in a human body in medical practice.</abstract><pub>Springer</pub><doi>10.1134/S1061934816070157</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1061-9348 |
| ispartof | Journal of analytical chemistry (New York, N.Y.), 2016-07, Vol.71 (7), p.737 |
| issn | 1061-9348 1608-3199 |
| language | eng |
| recordid | cdi_gale_infotracmisc_A496567850 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Analysis Blood serum High performance liquid chromatography Vitamin K |
| title | Determination of vitamin [K.sub.1] in blood serum by high-performance liquid chromatography |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T21%3A49%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Determination%20of%20vitamin%20%5BK.sub.1%5D%20in%20blood%20serum%20by%20high-performance%20liquid%20chromatography&rft.jtitle=Journal%20of%20analytical%20chemistry%20(New%20York,%20N.Y.)&rft.au=Sokolova,%20O.V&rft.date=2016-07-01&rft.volume=71&rft.issue=7&rft.spage=737&rft.pages=737-&rft.issn=1061-9348&rft.eissn=1608-3199&rft_id=info:doi/10.1134/S1061934816070157&rft_dat=%3Cgale%3EA496567850%3C/gale%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A496567850&rfr_iscdi=true |