Early relapse treatment ?

Background: Major depressive disorder (MDD) commonly takes a relapsing form. Transcranial magnetic stimulation (TMS) has be suggested as a means of maintaining remission. Brief courses of TMS at about monthly intervals appear to provide health benefits. Objective: To examine whether such brief cours...

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Veröffentlicht in:American journal of medical research (New York, N.Y.) N.Y.), 2017-04, Vol.4 (1), p.111
Hauptverfasser: Pridmore, Saxby, Erger, Sheila, Rybak, Marzena, Kelly, Erin, Lawson, Fiona
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container_issue 1
container_start_page 111
container_title American journal of medical research (New York, N.Y.)
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creator Pridmore, Saxby
Erger, Sheila
Rybak, Marzena
Kelly, Erin
Lawson, Fiona
description Background: Major depressive disorder (MDD) commonly takes a relapsing form. Transcranial magnetic stimulation (TMS) has be suggested as a means of maintaining remission. Brief courses of TMS at about monthly intervals appear to provide health benefits. Objective: To examine whether such brief courses of TMS are better conceptualized as maintaining remission, or as the provision of early relapse treatment. Method: 25 series of treatment (18 different patients) were considered. Pre- and post-treatment 6-item Hamilton Depression Rating Scale (HAMD6) and 7 visual analogue scales (VASs) were collected, along with pretreatment Clinical Global Impression-Severity (CGI-S) and post-treatment CGI-Improvement (I). Results: Pre-treatment HAMD6 and CGI-S indicated that many patients were symptomatic and in early relapse. Post-treatment HAMD6 indicated that many patients had achieved remission, and this was supported by the CGI-I. The VAS scores also improved. Conclusions: Short courses of TMS at about monthly intervals have beneficial results and are better conceptualized as early relapse treatment (ERT). Keywords: major depressive disorder; transcranial magnetic stimulation; early relapse treatment
doi_str_mv 10.22381/AJMR4120178
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Transcranial magnetic stimulation (TMS) has be suggested as a means of maintaining remission. Brief courses of TMS at about monthly intervals appear to provide health benefits. Objective: To examine whether such brief courses of TMS are better conceptualized as maintaining remission, or as the provision of early relapse treatment. Method: 25 series of treatment (18 different patients) were considered. Pre- and post-treatment 6-item Hamilton Depression Rating Scale (HAMD6) and 7 visual analogue scales (VASs) were collected, along with pretreatment Clinical Global Impression-Severity (CGI-S) and post-treatment CGI-Improvement (I). Results: Pre-treatment HAMD6 and CGI-S indicated that many patients were symptomatic and in early relapse. Post-treatment HAMD6 indicated that many patients had achieved remission, and this was supported by the CGI-I. The VAS scores also improved. Conclusions: Short courses of TMS at about monthly intervals have beneficial results and are better conceptualized as early relapse treatment (ERT). 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subjects Care and treatment
Development and progression
Magnetic brain stimulation
Major depressive disorder
Methods
Patient outcomes
Prevention
Recurrence (Disease)
Risk factors
title Early relapse treatment ?
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