Combination of .sup.1H NMR- and GC-MS-Based Metabonomics to Study on the Toxicity of Coptidis Rhizome in Rats

Coptidis Rhizome (CR), widely applied to treat with heat and toxicity, is one of the most commonly used traditional Chinese medicine (TCM), however, an extensive dosage can induce toxicity. Diarrhea is one of the most frequent side effects of CR treatment. In this study, metabonomics was combined wi...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e88281
Hauptverfasser:	Zhou, Yuting, Liao, Qiongfeng, Lin, Manna, Deng, Xuejiao, Zhang, Peiting, Yao, Meicun, Zhang, Lei, Xie, Zhiyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Body weight Complications and side effects Diarrhea Metabolites Microbiota (Symbiotic organisms) Physiological aspects Toxicity Traditional Chinese medicine
Online-Zugang:	Volltext
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