Toll-Like Receptor 3 Signalling Up-Regulates Expression of the HIV Co-Receptor G-Protein Coupled Receptor 15 on Human CD4.sup.+ T Cells

Many HIV-2 and SIV isolates, as well as some HIV-1 strains, can use the orphan 7-transmembrane receptor GPR15 as co-receptor for efficient entry into host cells. GPR15 is expressed on central memory and effector memory CD4.sup.+ T cells in healthy individuals and a subset of these cells is susceptib...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e88195
Hauptverfasser:	Kiene, Miriam, Rethi, Bence, Jansson, Marianne, Dillon, Stephanie, Lee, Eric, Lantto, Rebecka, Wilson, Cara, Pöhlmann, Stefan, Chiodi, Francesca
Format:	Artikel
Sprache:	eng
Schlagworte:	B cells Biological response modifiers Comparative analysis Health aspects HIV HIV infections Infection Interferon T cells
Online-Zugang:	Volltext
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