Loss of Dab2 Expression in Breast Cancer Cells Impairs Their Ability to Deplete TGF-[beta] and Induce Tregs Development via TGF-[beta]

Dab2 is a multifunctional adapter protein which is frequently under-expressed in a variety of cancers. It is implicated in many critical functions, including several signaling pathways, cell arrangement, differentiation of stem cells, and receptor endocytosis. Transforming growth factor-[beta] (TGF-...

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Veröffentlicht in:PloS one 2014-03, Vol.9 (3), p.e91709
Hauptverfasser: Xu, Shuguang, Zhu, Jingzhi, Wu, Zhiyong
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Sprache:eng
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