Post-Zygotic and Inter-Individual Structural Genetic Variation in a Presumptive Enhancer Element of the Locus between the IL10R[beta] and IFNAR1 Genes

Although historically considered as junk-DNA, tandemly repeated sequence motifs can affect human phenotype. For example, variable number tandem repeats (VNTR) with embedded enhancers have been shown to regulate gene transcription. The post-zygotic variation is the presence of genetically distinct po...

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Veröffentlicht in:	PloS one 2013-09, Vol.8 (9), p.e67752
Hauptverfasser:	Razzaghian, Hamid Reza, Forsberg, Lars A, Prakash, Kancherla Reddy, Przerada, Szymon, Paprocka, Hanna, Zywicka, Anna, Westerman, Maxwell P, Pedersen, Nancy L, O'Hanlon, Terrance P, Rider, Lisa G, Miller, Frederick W, Srutek, Ewa, Jankowski, Michal, Zegarski, Wojciech, Piotrowski, Arkadiusz, Absher, Devin, Dumanski, Jan P
Format:	Artikel
Sprache:	eng
Schlagworte:	Genes Genomes Genomics Transcription (Genetics)
Online-Zugang:	Volltext
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