A Powerful Yeast Model to Investigate the Synergistic Interaction of [alpha]-Synuclein and Tau in Neurodegeneration

Several studies revealed consistent overlap between synucleinopathies and tauopathies, demonstrating that [alpha]-synuclein (ASYN) and tau co-localize in neurofibrillary tangles and in Lewy bodies from Alzheimer's and Parkinson's disease patients and corresponding animal models. Additional...

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Veröffentlicht in:PloS one 2013-02, Vol.8 (2), p.e55848
Hauptverfasser: Ciaccioli, Gianmario, Martins, Ana, Rodrigues, Cátia, Vieira, Helena, Calado, Patrícia
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Sprache:eng
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