Aberrant Glycogen Synthase Kinase 3[beta] Is Involved in Pancreatic Cancer Cell Invasion and Resistance to Therapy

The major obstacles to treatment of pancreatic cancer are the highly invasive capacity and resistance to chemo- and radiotherapy. Glycogen synthase kinase 3[beta] (GSK3[beta]) regulates multiple cellular pathways and is implicated in various diseases including cancer. Here we investigate a pathologi...

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Veröffentlicht in:	PloS one 2013-02, Vol.8 (2), p.e55289
Hauptverfasser:	Kitano, Ayako, Shimasaki, Takeo, Chikano, Yuri, Nakada, Mitsutoshi, Hirose, Mayumi, Higashi, Tomomi, Ishigaki, Yasuhito, Endo, Yoshio, Takino, Takahisa, Sato, Hiroshi, Sai, Yoshimichi, Miyamoto, Ken-ichi, Motoo, Yoshiharu, Kawakami, Kazuyuki, Minamoto, Toshinari
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer prevention Chemotherapy Glycogen Glycogen synthesis Ionizing radiation Muscle proteins Pancreatic cancer Radiotherapy
Online-Zugang:	Volltext
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