Constitutive Phosphorylation of GATA-1 at Serine.sup.26 Attenuates the Colony-Forming Activity of Erythrocyte-Committed Progenitors

We previously reported that IL-3 signaling induces phosphorylation of GATA-1 at the serine.sup.26 position, which contributes to IL-3-mediated anti-apoptotic response. Here, we demonstrate that phosphorylation of GATA-1 at serine.sup.26 is also transiently induced in cells of the erythroid lineage (...

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Veröffentlicht in:	PloS one 2013-05, Vol.8 (5), p.e64269
Hauptverfasser:	Lin, Kou-Ray, Li, Chung-Leung, Yen, Jeffrey Jong-Young, Yang-Yen, Hsin-Fang
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Cytokines Erythropoietin Glutamate Transcription (Genetics)
Online-Zugang:	Volltext
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