Molecular Interpretation of ACTH-[beta]-Endorphin Coaggregation: Relevance to Secretory Granule Biogenesis

Peptide/protein hormones could be stored as non-toxic amyloid-like structures in pituitary secretory granules. ACTH and [beta]-endorphin are two of the important peptide hormones that get co-stored in the pituitary secretory granules. Here, we study molecular interactions between ACTH and [beta]-end...

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Veröffentlicht in:	PloS one 2012-03, Vol.7 (3), p.e31924
Hauptverfasser:	Ranganathan, Srivastav, Singh, Pradeep K, Singh, Uday, Singru, Praful S, Padinhateeri, Ranjith, Maji, Samir K
Format:	Artikel
Sprache:	eng
Schlagworte:	Beta endorphin Corticotropin Melanocyte stimulating hormone Molecular dynamics Oligomers
Online-Zugang:	Volltext
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