Ets-1 Is Essential for Connective Tissue Growth Factor Induction by TGF-[beta]1 in Osteoblasts

Background Ets-1 controls osteoblast differentiation and bone development; however, its downstream mechanism of action in osteoblasts remains largely undetermined. CCN2 acts as an anabolic growth factor to regulate osteoblast differentiation and function. CCN2 is induced by TGF-[beta]1 and acts as a...

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Veröffentlicht in:	PloS one 2012-04, Vol.7 (4), p.e35258
Hauptverfasser:	Geisinger, Max T, Astaiza, Randy, Butler, Tiffany, Popoff, Steven N, Planey, Sonia Lobo, Arnott, John A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone morphogenetic proteins Protein binding Transforming growth factors
Online-Zugang:	Volltext
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