Receptor Tyrosine Kinases Activate Canonical WNT/[beta]-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct [beta]-Catenin Phosphorylation

Receptor tyrosine kinase signaling cooperates with WNT/[beta]-catenin signaling in regulating many biological processes, but the mechanisms of their interaction remain poorly defined. We describe a potent activation of WNT/[beta]-catenin by FGFR2, FGFR3, EGFR and TRKA kinases, which is independent o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PloS one 2012-04, Vol.7 (4), p.e35826
Hauptverfasser:	Krejci, Pavel, Aklian, Anie, Kaucka, Marketa, Sevcikova, Eva, Prochazkova, Jirina, Masek, Jan Kukla, Mikolka, Pavol, Pospisilova, Tereza, Spoustova, Tereza, Weis, MaryAnn, Paznekas, William A, Wolf, Joshua H, Gutkind, J. Silvio, Wilcox, William R, Kozubik, Alois, Jabs, Ethylin Wang, Bryja, Vitezslav, Salazar, Lisa, Vesela, Iva, Balek, Lukas
Format:	Artikel
Sprache:	eng
Schlagworte:	Phenols (Class of compounds) Phosphotransferases Tyrosine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!