IL-1[alpha] Mediated Chorioamnionitis Induces Depletion of FoxP3+ Cells and Ileal Inflammation in the Ovine Fetal Gut

Endotoxin induced chorioamnionitis increases IL-1 and provokes an inflammatory response in the fetal ileum that interferes with intestinal maturation. In the present study, we tested in an ovine chorioamnionitis model whether IL-1 is a major cytokine driving the inflammatory response in the fetal il...

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Veröffentlicht in:	PloS one 2011-03, Vol.6 (3), p.e18355
Hauptverfasser:	Wolfs, Tim G. A. M, Kallapur, Suhas G, Polglase, Graeme R, Pillow, J. Jane, Nitsos, Ilias, Newnham, John P, Chougnet, Claire A, Kroon, Elke, Spierings, Julia, Willems, Coen H. M. P, Jobe, Alan H, Kramer, Boris W
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytokines Fatty acids Inflammation Protein binding RNA T cells
Online-Zugang:	Volltext
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