Endothelial and Macrophage-Specific Deficiency of P38[alpha] MAPK Does Not Affect the Pathogenesis of Atherosclerosis in ApoE.sup.-/- Mice

The p38[alpha] Mitogen-Activated Protein Kinase (MAPK) regulates stress- and inflammation-induced cellular responses. Factors implicated in the development of atherosclerosis including modified low-density lipoprotein (LDL), cytokines and even shear stress induce p38 activation in endothelial cells...

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Veröffentlicht in:	PloS one 2011-06, Vol.6 (6), p.e21055
Hauptverfasser:	Kardakaris, Rozina, Gareus, Ralph, Xanthoulea, Sofia, Pasparakis, Manolis
Format:	Artikel
Sprache:	eng
Schlagworte:	Apolipoproteins Atherosclerosis Cholesterol Cytokines Endothelium Inflammation Low density lipoproteins Macrophages Mitogens Protein kinases
Online-Zugang:	Volltext
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