NF[kappa]B1 and NF[kappa]BIA Polymorphisms Are Associated with Increased Risk for Sporadic Colorectal Cancer in a Southern Chinese Population

Nuclear factor [kappa]B (NF[kappa]B) plays a key role in the regulation of apoptosis. The function of NF[kappa]B is inhibited by binding to NF[kappa]B inhibitor (I[kappa]B), and disruption of the balance of NF[kappa]B and I[kappa]B is related to the development of many diseases, including tumors. Th...

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Veröffentlicht in:	PloS one 2011-06, Vol.6 (6), p.e21726
Hauptverfasser:	Song, Shunxin, Chen, Dianke, Lu, Jiachun, Liao, Jiawei, Luo, Yanxin, Yang, Zuli, Fu, Xinhui, Fan, Xinjuan, Wei, Yisheng, Yang, Lei, Wang, Lei, Wang, Jianping
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer research Colorectal cancer Development and progression Disease susceptibility Gene expression Genes Genetic aspects Risk factors
Online-Zugang:	Volltext
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