Spleen-Resident CD4.sup.+ and CD4.sup.- CD8[alpha].sup.- Dendritic Cell Subsets Differ in Their Ability to Prime Invariant Natural Killer T Lymphocytes

One important function of conventional dendritic cells (cDC) is their high capacity to capture, process and present Ag to T lymphocytes. Mouse splenic cDC subtypes, including CD8[alpha].sup.+ and CD8[alpha].sup.- cDC, are not identical in their Ag presenting and T cell priming functions. Surprisingl...

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Veröffentlicht in:PloS one 2011-10, Vol.6 (10), p.e26919
Hauptverfasser: Bialecki, Emilie, Macho Fernandez, Elodie, Ivanov, Stoyan, Paget, Christophe, Fontaine, Josette, Rodriguez, Fabien, Lebeau, Luc, Ehret, Christophe, Frisch, Benoit, Trottein, François, Faveeuw, Christelle
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Sprache:eng
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