Inside-Out Regulation of ICAM-1 Dynamics in TNF-[alpha]-Activated Endothelium

During transendothelial migration, leukocytes use adhesion molecules, such as ICAM-1, to adhere to the endothelium. ICAM-1 is a dynamic molecule that is localized in the apical membrane of the endothelium and clusters upon binding to leukocytes. However, not much is known about the regulation of ICA...

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Veröffentlicht in:	PloS one 2010-06, Vol.5 (6), p.e11336
Hauptverfasser:	van Buul, Jaap D, van Rijssel, Jos, van Alphen, Floris P. J, Hoogenboezem, Mark, Tol, Simon, Hoeben, Kees A, van Marle, Jan, Mul, Erik P. J, Hordijk, Peter L
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Antibodies Endothelium Integrins Muscle proteins Myosin Physiological aspects Polymerization Tumor necrosis factor
Online-Zugang:	Volltext
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