A Novel Role for the Centrosomal Protein, Pericentrin, in Regulation of Insulin Secretory Vesicle Docking in Mouse Pancreatic [beta]-cells

The centrosome is important for microtubule organization and cell cycle progression in animal cells. Recently, mutations in the centrosomal protein, pericentrin, have been linked to human microcephalic osteodysplastic primordial dwarfism (MOPD II), a rare genetic disease characterized by severe grow...

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Veröffentlicht in:	PloS one 2010-07, Vol.5 (7), p.e11812
Hauptverfasser:	Jurczyk, Agata, Pino, Steven C, O'Sullivan-Murphy, Bryan, Addorio, Martha, Lidstone, Erich A, diIorio, Philip, Lipson, Kathryn L, Standley, Clive, Fogarty, Kevin, Lifshitz, Lawrence, Urano, Fumihiko, Mordes, John P, Greiner, Dale L, Rossini, Aldo A, Bortell, Rita
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood glucose Cells (Biology) Insulin Pancreatic beta cells Proteins Type 2 diabetes
Online-Zugang:	Volltext
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