TGF-[beta].sub.1 As Possible Link between Loss of Bone Mineral Density and Chronic Inflammation

The TGF family plays a key role in bone homeostasis. Systemic or topic application of proteins of this family apparently positively affects bone healing in vivo. However, patients with chronic inflammation, having increased TGF-[beta].sub.1 serum-levels, often show reduced bone mineral content and d...

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Veröffentlicht in:	PloS one 2010-11, Vol.5 (11), p.e14073
Hauptverfasser:	Ehnert, Sabrina, Baur, Johannes, Schmitt, Andreas, Neumaier, Markus, Lucke, Martin, Dooley, Steven, Vester, Helen, Wildemann, Britt, Stöckle, Ulrich, Nussler, Andreas K
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone density Bone morphogenetic proteins Hip replacement arthroplasty Inflammation Osteoporosis Transforming growth factors
Online-Zugang:	Volltext
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