Transcription of AATATT Triplet Repeats in Escherichia coli Is Silenced by H-NS and IS1E Transposition

The trinucleotide repeats AAT*ATT are simple DNA sequences that potentially form different types of non-B DNA secondary structures and cause genomic instabilities in vivo. The molecular mechanism underlying the maintenance of a 24-triplet AAT*ATT repeat was examined in E.coli by cloning the repeats...

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Veröffentlicht in:PloS one 2010-12, Vol.5 (12), p.e14271
Hauptverfasser: Pan, Xuefeng, Liao, Yuanhong, Liu, Yunmeng, Chang, Peng, Liao, Lingni, Yang, Li, Li, Hongquan
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Sprache:eng
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