Dental Calculus Stimulates Interleukin-1[beta] Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes

Dental calculus is a mineralized deposit associated with periodontitis. The bacterial components contained in dental calculus can be recognized by host immune sensors, such as Toll-like receptors (TLRs), and induce transcription of proinflammatory cytokines, such as IL-1[beta]. Studies have shown th...

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Veröffentlicht in:	PloS one 2016-09, Vol.11 (9), p.e0162865
Hauptverfasser:	Montenegro Raudales, Jorge Luis, Yoshimura, Atsutoshi, SM, Ziauddin, Kaneko, Takashi, Ozaki, Yukio, Ukai, Takashi, Miyazaki, Toshihiro, Latz, Eicke, Hara, Yoshitaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystal structure Enzyme-linked immunosorbent assay Hydroxyapatites Interleukins Lipids Macrophages
Online-Zugang:	Volltext
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