T-catenin in restricted brain cell types and its potential connection to autism

Background Recent genetic association studies have linked the cadherin-based adherens junction protein alpha-T-catenin ([alpha]T-cat, CTNNA3) with the development of autism. Where [alpha]T-cat is expressed in the brain, and how its loss could contribute to this disorder, are entirely unknown. Method...

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Veröffentlicht in:	Journal of Molecular Psychiatry 2016-06, Vol.4 (1)
Hauptverfasser:	Folmsbee, Stephen Sai, Wilcox, Douglas R, Tyberghein, Koen, De Bleser, Pieter, Tourtellotte, Warren G, van Hengel, Jolanda, van Roy, Frans, Gottardi, Cara J
Format:	Artikel
Sprache:	eng
Schlagworte:	Autism Brain GABA Genetic aspects Nervous system diseases Neurons
Online-Zugang:	Volltext
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