IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGF[beta] Release

Immunomodulatory Foxp3.sup.+ regulatory T cells (Tregs) form a heterogeneous population consisting of subsets with different activation states, migratory properties and suppressive functions. Recently, expression of the IL-33 receptor ST2 was shown on Tregs in inflammatory settings. Here we report t...

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Veröffentlicht in:	PloS one 2016-08, Vol.11 (8), p.e0161507
Hauptverfasser:	Siede, Julia, Fröhlich, Anja, Datsi, Angeliki, Hegazy, Ahmed N, Varga, Domonkos V, Holecska, Vivien, Saito, Hirohisa, Nakae, Susumu, Löhning, Max
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell proliferation Interleukins T cells Transforming growth factors
Online-Zugang:	Volltext
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